Noncovalent interactions (NCIs) are ubiquitous in Nature and contribute to the cohesion of chemical systems. In comparison to covalent bonds, intra- and intermolecular noncovalent interactions are in general locally weak and exhibit much lower energy and directionality. Nevertheless, in many cases these interactions can collectively play a dominant role in synthesis, catalysis and design of materials. Based on the nature of the particular elements or synthons involved NCIs are often classified into subclasses of bonds and interactions.

This Joint Special Collection published by Chemistry – A European Journal, ChemPlusChem, EurJIC and EurJOC in collaboration with the Chemistry Europe ( showcases the latest developments in research on NCIs and their applications. Invited contributions and selected papers by the Plenary Lecturers and IAB members are featured here.